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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5ea16e6910b784be94dbf2ed664e65ca08c712e66a70a338cf0f5f21b79bf3b' 
  AND token = '3aVm5LNojyD+Y6bYDSyMr7Gh5ERTBnicxF7Po8Xd5uY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}