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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e951057f7edce0e2774a42c089f48128d1618546d47ea8bd0739ea17b1a0d664' 
  AND token = 'wmQN32MbqY1mL/h8g6d72sBoqCpdbqRdxo9yZv65tRY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}