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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cba5c0f4158336db8e0360c447f9c4034863d33a3b9761a92192313e4d76fa6' 
  AND token = 'PnuK+QF52ScpMd+3Q0TOd9lwPPaxzkeCK77KuQPmLfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}