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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ab00a7f3e6bf7e84eb70096e6e07b2344cfe7a96a6f13044896ab85c38d7da0' 
  AND token = 'Az0D+a2emIZXpGRJ1mDTPjtsTkEdNFFcfvXE1C0+XvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}