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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '455052683d0b161e12abc4da6cef97913e6b6dc0fed9e45238ada61c4811d649' 
  AND token = 'vHCsIIAf51vki9WL9ASVz+PAYCWL0/GYML/wxj6Y+iE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}