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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10de6621a0146e191147760d6340cf2dfe9253d7046c1026227a362956355472' 
  AND token = 'ITET6HLZhfjuxoq7R/j0fwm8JRI6SBz3atcsPtyGQ7E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}