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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37a72d0de5dcc183e10b160f46880ab49bfc7b7b8bf941b9110dd7335256ff0a' 
  AND token = 'tgdTQmc2/w2A7A+uC3luEzZ+SWRkf6C1YZK7FUf4zWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}