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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c89cd6ed2de10d2d758d5d69a41221b10198bccd92efef8fead7952a0e3d48f7' 
  AND token = 'NM1eoTQEEU9KnCVsPuNpcTJ8IY7CwLPcVzX38+K7MAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}