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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81be0144d82e7b227bccd2c622ff1d2c0f66fa5cbc859d89940d7c222151bff5' 
  AND token = 'T3QBV3ZZ2aZCyyoMdnRCCFJKQyy3UUmVW66VdIPU2sU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}