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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54b08e910995d8e5095b6c45a1fc270c75411586f3c8cbbdd22add9a7eda54f5' 
  AND token = 'NU2kJbwtg0z4g/CV00RgKkt3vvuqcmxzrtj5vWWPCzs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}