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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28193f73d92d275199223baf33da1a9edc04a52a0a84ca1b60728a799f721350' 
  AND token = 'XjXjRnApuVxn0FHyj9dX64yaSBN5JE+m1aeWAfA2Qhg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}