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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45b4cf53324cef2bf451f65bfc50555d0cd150ec1ab4b116169ef5504abd4c45' 
  AND token = 'oTklP+EFXTckx+waDiP5kz5sGWq2gEsUelfoO4Vb60M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}