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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4e8209881fd08af9983db2c3d3f7299b1748d8f8f15b0d82553e172e47ffc10' 
  AND token = 'wY1n/ZOizFuMRZ0+BrpCqcmZSdTm7nbWb+ZjxjMpWdE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}