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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '133281bc014b684eb0512001521cf5fc0055f3fc282070e46abb13a04b83c82a' 
  AND token = '6H+WU/kiesH0sA6op3Be7TihH3zMGrm1qMEGvpV9aDw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}