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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6c687d544302ef32085754434b2d14fa54384961b8691f51e74dadb140c18b1' 
  AND token = 'nsUXC9Foc1PT3BJzK6tGTiZI0IkPtn8uvt+sHdf3Aqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}