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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a48112598c289c25878b47d049e7fec82ab366e4e0336de31ac7e8fd63cb1856' 
  AND token = 'mWGJx+3Puigv02tfv6vuXzCd6fEvlBZv0qeG8JzZuF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}