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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6058e88e2a76d1204625931496f6ad9a2fbcaee80b1649dedc28d948fc135c22' 
  AND token = 'Krg3rq+v/Khv2O/1vBnWLCC4QmnXl1xTy7Xpd0KePEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}