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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21eda9001f4fd5afc3e7f3ba3b5b3bb09636ab8e86120845acac9adcf7caf02f' 
  AND token = '+ieu32tdmSDEHV4wiH1MAcUs8vVfkXn6Y7cdrLlkr8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}