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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00ad35e2027d06da2f5a546e32805dcbe61aec4d49eb6bb4f3cb8acd5f065d2f' 
  AND token = 'F2v15T4UCHnDntEbFRQAERz/ZPQqW/f4i0d4WQ8mVhk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}