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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '374b1eb5edaa04d7a2e53be71f9dfff8e3160dda64687cc8826f23a5f3170101' 
  AND token = 'dE+vORwANMsUMPu1uEeeYiNPY8MtKJjkMT82WV4yrPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}