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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f91678cf575381d722458eefbc67b607cad2a0028aa0f0ad98f3b018b27b644' 
  AND token = 'ex2CRWDRiSBMa9HhWTQa+cxAHpV+bJI1OKg9669LSd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}