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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2da5711d6de5924eb5871591b74d573b9271747b778670e68a0bd9a03232a0b2' 
  AND token = '+VX9MDd0/Xj/V2bj0f2kaHp3Hg7x99cQFxY/y158wrg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}