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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '188e79ff54c6f8da700cd86a72196b9c0079e95b52e8d04449a3250e1cf56830' 
  AND token = '+yRPEQLmoOmDq9atxqBO+s+uyntG1R6wHOIVNVo42jc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}