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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8e42b76e601eec718d54dfb70644fd2a35413ce99179155339a5dba2be2d287' 
  AND token = 'ZAqMg2mbqJ262s2RH7R+UL2o9EJrPZSAhA9sBteVaeM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}