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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b0ed727b82a537e47cb2e747d05d6f948d3b458cbc3d196b7729b20f3b2527f' 
  AND token = 'eS9KHmRFN6rXK2UEuh6VdIxWY08I+gqGfoQh9imAwH8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}