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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64143c823e038227a8aa46950ec1b49d6b0d9c62ee7a1eed213b849e013e741b' 
  AND token = 'qdSq4u1/Y5f7UO5MvzBLFrP6S5lDe8Az2Y6o9fQzQyw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}