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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9181296e01a54a57a06f7bf059852757b3988ed5ef3a7e7f102c33175932d07' 
  AND token = 'atY2yKVKQ0f6FMT9HZmGIqXxUlET+wEK6qdGZJE2/20=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}