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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd201187d75e1f1bff0720cf854270ea1cce2aa25896c5822708bc67bece80822' 
  AND token = 'Exq95XiTDOG+ZCZ3o7JCPdviHOUX37Sl6FqQZBeN6A0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}