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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43a5a1399b348e6e4e580dbe0c1a0fbf66006db40a2b0e2712f6bf7a94941085' 
  AND token = '2sK1jtfUdaMjkZNF9/2xbT1ZdplZHbUooc9TTFIKVJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}