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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ef727a37aef66d0cf9137fd83d2a3a14a51b8d8940aa9d527da96fd418a3441' 
  AND token = 'CK3HE97txtKp24p6UcaYPP52fLB1Zh32grM1c5i+ZHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}