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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8b0ba7e6a1506b9f255d89db0523ebeeff008c0e9dc7c37b5365196b2ec1973' 
  AND token = 'M7yGsc88E2170uNOCzSNYj9g+UYXhqKHnXAgRqI1fT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}