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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e20b9b02887c3d47749624baf8752f266a6c1093c34be2b7efd766db30a15336' 
  AND token = 'HUUlBUMC1TC+p2osYu/+FGxBX3RGRYN45OkCDDEN66k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}