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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75b25035bb8d9db6f3a84d600bd3f59843c8220495890ed3ae57b331fdfc7378' 
  AND token = '0OaR99eUmIkj62h4JyZRG9A4WagSnO6Dyd0+5IoonCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}