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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5165573fe1e02de5fa38a34d90610f24863deb2eb2b886e8969fe3bfd9403592' 
  AND token = 'aG9hR5oOwO8Dd+nysDL8sYq/2atILEFtOVwPf/3orTE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}