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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7704b94d778c27276bb005a48b0dad6d547fb9812b295f9d6c26854123969aad' 
  AND token = '3ynQsigVEGex8oaO8WUsSSx+VtQgyg4DGhHJkuDh9Cs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}