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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df1aa53b0329420941a71259c1ab8b54e12d35b251cbf04baf34ff9470feb653' 
  AND token = '6w9JDH8MrTFyX1zTMU4RK3I9PdL035Rvqldg1TMm6Eo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}