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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22be25bc44f4e58aee577fbb13681c1451cebef220c3142f522acece0c2e64f1' 
  AND token = 'n/NADz7BjtTv0NVoQNGxZ3YGFoXK0m9B/Q7OyFB3510=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}