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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de4f075e7bb309d0cac4a1c6d99f0ba6686b6e6d260045da39c2fc0a78c8a069' 
  AND token = 'fnWm9kOgNtuD1VGZfxgo8RA6xiCeiPyc2wyNDQ6LztU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}