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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3df6f1987287290287d82a0cde644031066b65d5c6efbaf607ef709838d1366c' 
  AND token = 'ipAevxFNyEXsprXnaYwtw96kwPEf3QWAoGe5yL33vcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}