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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e86252d3233dc82d914e2afb3a6906cbda87cd0d72534259e484b4383edef1c1' 
  AND token = 'vCp1BMBJohtN+N913YrkimlDkS05YUVDV0b5GIdLgBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}