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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dd8f2364c8df61227bd2e5a99a17a88987cee947cbd36c4ca6081a1c4f1ad16' 
  AND token = '9StVql9QpKxc+mAp2MqGymFPMb1w6PluaWmMRrPys6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}