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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7776c19a2a1e8d0be259333f38af35a0a924ae7635e0a92dcadbf30556c421c3' 
  AND token = 'W/uTWIAZtWD1Ro0nlFfcJNFXlP4zEsCjZzTXe6+FROY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}