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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6949e03f18a9ac069a77dd9d79b00d8f750309969d714b1515c5df1a66f83d96' 
  AND token = '+koHv1f5tg5rSM3RaJXRjOehOuue1qs7wB6+mqsgNZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}