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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8348e89f7ef436d6b8f8e182be9af31824b22033f280bab2ba575cc0ab357f7d' 
  AND token = 'b21M3YLKoiOWc3akiX+Gerg0qRpyRQ/FDlaDA32Lo5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}