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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '222158ac1d0e79fbcbe9de618179a231cbd47c0314d46a699bea60b88bd13375' 
  AND token = 'Tcsva4M3ID8HZIB6eBJJ1bQUzPVO//W+4oMuvDnZ8YU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}