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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12c8be5c0439f0699de29eb74d49df8a9efa398a2e7d0bed0fd1c11a2c4228d2' 
  AND token = 'SyyL+msvBMpq4Hzen+TJqRWMcfofq3FiwgxRE4YjUYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}