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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9df5a6e89ec480b432f837b7e861069eaf49138c18d9690ec0db185c4e391a17' 
  AND token = 'BMx1UkDq2eLwI9lq6eBy49nCOojeg/g+14HY8TLa6Gs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}