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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b44abb6b3baf52e49592f725f077e2555213108fd08c66911a03ab961e50cec1' 
  AND token = 'aZBtFpcCp60smoyLAqS5Tp3uxQjnoRHi3TwCRZxjdj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}