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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8df247e0d67da085a99cd07521f4156d5e86d26bc9f5b8a47d6592e026512b7b' 
  AND token = 'w/9emah7F3QIKssL+wbS3tfQiS7xIMcehyag5/JhD1M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}