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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1e05e45087d6c09f205170ae82187af3bdf5002763b06d6a15c6fb5aedc4aed' 
  AND token = 'r9wDoICKOqS3qedijwQk7x0Xd4X+zUhpk46YoxWjBgA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}